Adjusting Cell-Surface Interactions Through a Covalent Immobilization of Biomolecules
Z przyjemnością informujemy, że nasz najnowszy artykuł przeglądowy właśnie pojawił się na łamach czasopisma Advanced Materials Interfaces!
Adjusting Cell-Surface Interactions Through a Covalent Immobilization of Biomolecules
Development of multifunctional, bio-active surfaces has become a major focus of biomedical engineering in the last decade. By using physicochemical surface modification technique, it is possible to equip biomedical surfaces with numerous properties, including enhanced cell proliferation and adhesion, as well as antibacterial or anti-inflammatory effects. Covalent immobilization, particularly, is a favorable strategy to form long-lasting biomedical coatings with versatile biological activity stable over time. This review combines an overview of current and emerging immobilization techniques coupled with an in-depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules.
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