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New NCN-Sonata bis project: controlled release of neurotransmitters
Neurological disorders are the third most common cause of disability and premature death in EU, and the number of patients is expected to grow intensively over the next years. The most common neurological disorders are associated with the malfunction in the delivery of neurotransmitters – chemical messengers that transmit a signal from a neuron across the synapse to a target cell.
Researchers associated with POB1 are going to design a neurotransmitter-loaded material that will be able to release neurotransmitter molecules in a highly controlled, electrically-triggered manner. The material will be used as a neural electrode coating, to allow neurotransmitter to be released directly in the nervous system. To prevent neurotransmitter from spontaneous release, developed material will exhibit a multi-layer structure, with consecutive layers differing in neurotransmitter permeability.
The project entitled "Multilayer electroactive coatings with hierarchical structure for controlled delivery of neurotransmitters, supervised by dr hab. inż. Katarzyna Krukiewicz, assoc. prof., has been funded in the framework of NCN Sonata Bis programme.