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Author: Katarzyna Krukiewicz Published at: 08.12.2021 Last update: 08.12.2021

POB1 Seminar: Prof. Simon Tavaré

Our guest of the next POB1 Seminar is Prof. Simon Tavaré (Columbia University, NY, USA), a renowned expert in the field of computational genomics. His research profile is available here.

Prof. Tavaré will give an overview of three ongoing projects in his lab in the area of computational genomics, varying from large scale to small. The first is the IMAXT project funded by Cancer Research UK’s Grand Challenge competition (now called Cancer Grand Challenges, and jointly supported by CRUK, the National Cancer Institute and others). He and his team have been developing the technology to molecularly annotate cells in a tumor with spatial resolution. Prof. Tavaré will demonstrate the VR system that his collaborators at Suil Interactive have developed to allow investigators to view the same tumor simultaneously. The second is a project to identify biomarkers from RNAseq experiments to predict response to checkpoint inhibitors. The third, which is motivated by allele frequency counts from covid sequencing data, concerns modeling “counts of counts” data (known as the allele frequency spectrum in genetics). The last project is very much in its infancy, and there are opportunities for new modeling approaches.

The seminar will be held by prof. Marek Kimmel.

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